Bioss Inc.'s ACTN2 (7G3) Monoclonal Antibody is a Rabbit monoclonal antibody. The ACTN2 (7G3) Monoclonal Antibody was generated using Actinin alpha 2, and Actn2 as the antigen. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Precipitation, Immunohistochemistry, Immunohistochemistry - fixed, Immunoprecipitation, and Western Blot.
Description
ACTN2 is a member of the alpha-actin binding protein gene family. ACTN2 is primarily expressed in skeletal muscle and functions as a structural component of the sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status. ACTN2 is an F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. ACTN2 is a bundling protein